PCNA (PC10)anticorps
Santa Cruz Biotechnology
Catalogue: sc-56

total number of products: 8

souris monoclonal (PC10)
Réactivité: tiger salamander, , axolotl, ring-tailed coati, African green monkey, medaka, humain, souris, rat, poulet, Sus Sucidés
application: Western blot, immunohistochimie, immunocytochimie, immunoprécipitation, cytométrie en flux, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section, proximity ligation assay
citations: 431

quantité: 200 µg/ml
Prix: 279 USD
fournisseur

PCNA (F-2)anticorps
Santa Cruz Biotechnology
Catalogue: sc-25280

total number of products: 8

souris monoclonal (F-2)
Réactivité: , humain, souris, rat
application: Western blot, ELISA, immunohistochimie, immunocytochimie, immunoprécipitation, immunohistochemistry - paraffin section
citations: 49

quantité: 200 µg/ml
Prix: 279 USD
fournisseur

PCNA (PC10)AC
Santa Cruz Biotechnology
Catalogue: sc-56 AC

total number of products: 8

souris monoclonal (PC10)
Réactivité: humain, souris, rat
application: Western blot, immunohistochimie, immunocytochimie, immunoprécipitation, proximity ligation assay
citations: 29

quantité: 500 µg/ml, 25% ag
Prix: 366 USD
fournisseur

PCNA anticorps monoclonal(PC10)
Invitrogen
Catalogue: MA5-11358

total number of products: 7

souris monoclonal (PC10)
Réactivité: Domestic guinea pig, marsh frog, Nile tilapia, budgerigar, Hamsters, Pacific oyster, fission yeast, humain, souris, rat, chien, poulet, Sus Sucidés, poisson-zèbre , mouton, platanna, lapin
application: Western blot, immunohistochimie, immunocytochimie, immunoprécipitation, cytométrie en flux, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 190

Formalin-fixed, paraffin-embedded human small intestine stained with Proliferating Cell Nuclear Antigen antibody using peroxidase-conjugate and DAB chromogen. Note nuclear staining of proliferating cells. Formalin-fixed, paraffin-embedded rat breast cancer stained with PCNA antibody using peroxidase-conjugate and AEC chromogen. Note nuclear staining of tumor cells.
quantité: 500µL
Prix: US 309.00
fournisseur

PCNA Monoclonal Antibody (PC10 (a.k.a. 3F81)), eBioscience™
Invitrogen
Catalogue: 14-9910-82

total number of products: 7

souris monoclonal (PC10 (a.k.a. 3F81))
Réactivité: humain, souris, rat
application: Western blot, immunohistochimie, immunocytochimie, immunoprécipitation, cytométrie en flux
citations: 4

quantité: 100µg
Prix: US 129.00
fournisseur

PCNA Monoclonal Antibody (PC10 (a.k.a. 3F81)), eFluor 615, eBioscience™
Invitrogen
Catalogue: 42-9910-82

total number of products: 7

souris monoclonal (PC10 (a.k.a. 3F81))
Réactivité: humain, souris, rat
conjugué: eFluor 615
application: immunohistochimie, immunocytochimie
citations: 4

quantité: 100µg
Prix: US 274.00
fournisseur

PCNA antibody [PC10] - Proliferation Marker
Abcam
Catalogue: ab29

souris monoclonal (PC10)
Réactivité: humain, souris, rat, poulet, Sus Sucidés, poisson-zèbre , drosophile
application: Western blot, immunohistochimie, immunocytochimie, immunoprécipitation, cytométrie en flux, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section, proximity ligation assay, bloque ou active expériences
citations: 143

quantité: 100 ug
Prix:
fournisseur

Rabbit polyclonal to PCNA
Abcam
Catalogue: ab18197

lapin polyclonal
Réactivité: humain, souris, rat, vaches, poisson-zèbre , platanna
application: Western blot, immunohistochimie, immunocytochimie, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 31

quantité:
Prix:
fournisseur

PCNA anticorps
Abcam
Catalogue: ab140877

chèvre polyclonal
Réactivité: humain, rat, poulet, vaches
application: Western blot
citations: 1

quantité: 200 ul
Prix:
fournisseur

PCNA
Proteintech Group
Catalogue: 10205-2-AP

lapin polyclonal
Réactivité: humain, souris, rat, poisson-zèbre
application: Western blot, ELISA, immunohistochimie, immunocytochimie, immunoprécipitation, cytométrie en flux
citations: 71

The PCNA antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PCNA. This antibody recognizes human,mouse,rat,zebrafish antigen. The PCNA antibody has been validated for the following applications: ELISA, IF, IP, WB, FC, IHC analysis.
quantité: 150 ul
Prix: 99 USD
fournisseur

PCNA
Proteintech Group
Catalogue: 60097-1-Ig

souris monoclonal (10D10E11)
Réactivité: humain, souris, rat
application: Western blot, ELISA, immunohistochimie, immunocytochimie, immunoprécipitation, cytométrie en flux
citations: 7

The PCNA antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human PCNA. This antibody recognizes human, mouse, pig, rat antigen. The PCNA antibody has been validated for the following applications: ELISA, FC, IF, IHC, IP, WB analysis.
quantité: 150 ul
Prix: 99 USD
fournisseur

PCNA
Proteintech Group
Catalogue: 24036-1-AP

lapin polyclonal
Réactivité: humain, souris, rat
application: Western blot, ELISA, immunohistochimie, immunocytochimie, immunoprécipitation, immunohistochemistry - paraffin section
citations: 1

The PCNA antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PCNA. This antibody recognizes human, mouse, rat antigen. The PCNA antibody has been validated for the following applications: ELISA, WB, IHC, IP, IF analysis.
quantité: 150 ul
Prix: 279 USD
fournisseur

Purified anti-human/mouse/rat PCNA
BioLegend
Catalogue: 307901

total number of products: 7

souris monoclonal (PC10)
Réactivité: humain, souris, rat
application: Western blot, immunohistochimie, immunoprécipitation
citations: 14

quantité: 25 μg
Prix: 50 USD
fournisseur

Alexa Fluor® 594 anti-human/mouse/rat PCNA
BioLegend
Catalogue: 307914

total number of products: 7

souris monoclonal (PC10)
Réactivité: humain, souris, rat
conjugué: Alexa Fluor 594
application: immunohistochemistry - paraffin section
citations: 13

quantité: 100 μg
Prix: 225 USD
fournisseur

Biotin anti-human/mouse/rat PCNA
BioLegend
Catalogue: 307904

total number of products: 7

souris monoclonal (PC10)
Réactivité: humain, souris, rat
conjugué: biotine
citations: 7

quantité: 100 μg
Prix: 190 USD
fournisseur

PCNA anticorps[PC10]
GeneTex
Catalogue: GTX20029

souris monoclonal (PC10)
Réactivité: humain, souris, rat
application: Western blot, immunohistochimie, immunocytochimie, immunoprécipitation, FACS, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 10

Western blot analysis of HeLa Nuclear Extract probed with Mouse anti Human PCNA (GTX20029)

Staining of KM-H2 cells with MOUSE ANTI PCNA:FITC (GTX75144)following permeabilisation

Human Tonsil stained with Anti-CD3, T Cell at a 1:150 dilution (red) and Monoclonal Anti-Proliferating Cell Nuclear Antigen (GTX20029) at a 1:500 dilution (green). Counterstained with DAPI.
quantité: 100.00μg
Prix: 299 USD
fournisseur

PCNA anticorps
GeneTex
Catalogue: GTX100539

lapin polyclonal
Réactivité: humain, souris, rat
application: Western blot, immunohistochimie, immunocytochimie, immunohistochemistry - paraffin section
citations: 9

PCNA antibody detects PCNA protein by western blot analysis. A. 30 ?g NIH-3T3 whole cell lysate/extract 12 % SDS-PAGE PCNA antibody (GTX100539) dilution: 1:2500

PCNA antibody detects PCNA protein by western blot analysis. A. 30 ?g PC-12 whole cell lysate/extract 12 % SDS-PAGE PCNA antibody (GTX100539) dilution: 1:2500

Immunohistochemical analysis of paraffin-embedded breast ca, using PCNA(GTX100539) antibody at 1:100 dilution.
quantité: 100.00μl
Prix: 299 USD
fournisseur

PCNA anticorps(PC10)
Novus Biologicals
Catalogue: NB500-106

total number of products: 18

souris monoclonal (PC10)
Réactivité: fish, primates, humain, souris, rat, poulet, poisson-zèbre
application: Western blot, ELISA, immunohistochimie, immunocytochimie, immunoprécipitation, cytométrie en flux, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 16

Immunohistochemistry-Frozen: PCNA Antibody (PC10) [NB500-106] - IHC analysis of a paraformaldehyde fixed frozen section of brain from murine embryo using PCNA antibody clone PC10 (green), an IB4 antibody (red) and DAPI. Image provided by Dr Siegenthaler via product review.

Immunohistochemistry-Paraffin: PCNA Antibody (PC10) [NB500-106] - Analysis of paraffin-embedded human colon carcinoma, showing nuclear localization.

Western Blot: PCNA Antibody (PC10) [NB500-106] - Analysis of human (HeLa lysate), murine (SV-T2 lysate), bovine (BAEC lysate), and porcine (PAE lysate) cell extracts.
quantité: 0.1 ml
Prix: 329 USD
fournisseur

PCNA anticorps(SPM350)
Novus Biologicals
Catalogue: NBP2-32989

total number of products: 18

souris monoclonal (SPM350)
Réactivité: humain, souris, rat, poulet, poisson-zèbre
application: Western blot, immunocytochimie, immunoprécipitation, cytométrie en flux, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

Immunohistochemistry-Paraffin: PCNA Antibody (SPM350) [NBP2-32989] - Formalin-paraffin human tonsil stained with PCNA MAb (SPM350)
quantité: 0.2 mg
Prix: 299 USD
fournisseur

Mouse Monoclonal PCNA Antibody (PC10) [Alexa Fluor® 405]
Novus Biologicals
Catalogue: NB500-106AF405

total number of products: 18

souris monoclonal (PC10)
Réactivité: humain, souris, rat, poulet, poisson-zèbre
conjugué: Alexa Fluor 405
application: Western blot, ELISA, immunohistochimie, immunocytochimie, immunoprécipitation, cytométrie en flux, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

quantité: 0.1 ml
Prix: 369 USD
fournisseur

PCNA
Epitomics
Catalogue: 2714-1

lapin monoclonal
Réactivité: humain, souris, rat
application: Western blot, immunohistochimie, immunocytochimie, immunoprécipitation, immunohistochemistry - paraffin section
citations: 6

quantité: 100 ul
Prix:
fournisseur

PCNA polyclonal anticorps
Bioss
Catalogue: bs-0754R

total number of products: 6

lapin polyclonal
Réactivité: humain, souris, rat
application: Western blot, immunocytochimie, immunohistochemistry - paraffin section
citations: 2

Formalin-fixed and paraffin embedded rat thymus tissue labeled Anti-PCNA Polyclonal Antibody, Unconjugated (bs-0754R) at 1:200, followed by conjugation to the secondary antibody and DAB staining
quantité: 100 ul
Prix: 279.5 USD
fournisseur

PCNA-Proliferation Marker Antibody
Bioss
Catalogue: bs-2006R

total number of products: 6

lapin polyclonal
Réactivité: humain, souris, rat
application: Western blot, immunocytochimie, immunohistochemistry - paraffin section
citations: 1

Formalin-fixed and paraffin embedded human oral squamous cell carcinoma labeled with Anti- PCNA-Proliferation Marker Polyclonal Antibody, Unconjugated (bs-2006R) at 1:100 followed by conjugation to the secondary antibody and DAB staining

Formalin-fixed and paraffin embedded human brain tissue labeled with Anti-PCNA Polyclonal Antibody, Unconjugated (bs-2006R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Formalin-fixed and paraffin embedded human glioma tissue labeled with Anti-PCNA Polyclonal Antibody, Unconjugated (bs-2006R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
quantité: 100 ul
Prix: 269 USD
fournisseur

PCNA (1C11)anticorps monoclonal
Bioss
Catalogue: bsm-2006M

total number of products: 6

souris monoclonal (1C11)
Réactivité: humain, rat
application: Western blot, immunocytochimie, immunohistochemistry - paraffin section
citations: 1

quantité: 100 ul
Prix: 279.5 USD
fournisseur

anti-Proliferating Cell Nuclear Antigen (PCNA) antibody
Antibodies-online
Catalogue: ABIN1108598

souris monoclonal (IML-83)
Réactivité: humain, souris, rat
application: Western blot, immunohistochimie, immunocytochimie, immunohistochemistry - frozen section
citations: 3

quantité: 0.1 mg
Prix: 313.5 USD
fournisseur

MOUSE ANTI PCNA:FITC
Bio-Rad
Catalogue: MCA1558F

souris monoclonal (PC10)
Réactivité: rat, chien
conjugué: FITC
application: cytométrie en flux
citations: 1

quantité: 0.1 mg
Prix: 265 USD
fournisseur

MOUSE ANTI PCNA:HRP
Bio-Rad
Catalogue: MCA1558P

souris monoclonal (PC10)
Réactivité: rat
conjugué: HRP
application: Western blot

quantité: 0.1 mg
Prix: 265 USD
fournisseur

PCNA anticorps
StressMarq Biosciences
Catalogue: SPC-1307D

lapin polyclonal
Réactivité: humain, souris, rat
application: Western blot, ELISA, immunohistochimie

quantité: 100 µl
Prix: 255.00 USD
fournisseur

Proliferating cell nuclear antigen monoclonal antibody (PC10)
Enzo Life Sciences
Catalogue: ALX-801-091-L001

souris monoclonal (PC10)
Réactivité: humain, souris, rat, chien
application: immunohistochimie

quantité: 1 ml
Prix: 645 USD
fournisseur

PCNA anticorps
Abbexa
Catalogue: abx013174

lapin polyclonal
Réactivité: humain, souris, rat
application: Western blot, ELISA, immunohistochimie

quantité: 100 μg
Prix: 266 USD
fournisseur

Anti-PCNA Antibody [PC10]
OriGene
Catalogue: TA309795

total number of products: 6

souris monoclonal (PC10)
Réactivité: humain, souris, rat, poulet
application: Western blot, immunohistochimie

quantité: 0.1 ml
Prix: 325 USD
fournisseur

Anti-PCNA Antibody
OriGene
Catalogue: TA312025

total number of products: 6

lapin polyclonal
Réactivité: humain, souris, rat
application: Western blot, immunohistochimie

quantité: 100 ul
Prix: 325 USD
fournisseur

Anti-PCNA Antibody
OriGene
Catalogue: TA319162

total number of products: 6

lapin polyclonal
Réactivité: humain, souris, rat, chien, poulet, vaches
application: Western blot

quantité: 100 ug
Prix: 325 USD
fournisseur

Anti-PCNA monoclonal antibody, clone QD21 [FITC]
Creative Biomart
Catalogue: DCABH-9564

souris monoclonal (QD21)
Réactivité: humain, souris, rat, poulet, poisson-zèbre , drosophile
conjugué: FITC
application: immunocytochimie

quantité: 100 μg
Prix:
fournisseur

Anti-PCNA monoclonal antibody, clone 327 (QD20)
Creative Biomart
Catalogue: DCAB-TJ025

souris monoclonal (327 (QD20))
Réactivité: humain, rat
application: immunohistochimie, immunocytochimie

quantité: 7.0 ml
Prix:
fournisseur

Rabbit Polyclonal to Human PCNA / Cyclin
MyBioSource
Catalogue: MBS240535

lapin polyclonal
Réactivité: humain, souris, rat, chien, poulet, vaches
application: Western blot, ELISA, immunohistochimie, dosage immuno-enzymatique

quantité: 0.05 mg
Prix: 495 USD
fournisseur

PCNA polyclonal anticorps
MyBioSource
Catalogue: MBS125201

lapin polyclonal
Réactivité: humain, souris, rat
application: Western blot, immunohistochimie, immunocytochimie, immunoprécipitation

quantité: 0.05 mL
Prix: 230 USD
fournisseur

PCNA (C19)anticorps
MyBioSource
Catalogue: MBS440048

lapin polyclonal
Réactivité: humain, souris, rat
application: Western blot, immunohistochimie, immunoprécipitation

quantité: 0.2 mg
Prix: 240 USD
fournisseur

Anti-PCNA Antibody (clone PC10) IHC-plus™ LS-B3434
LifeSpan Biosciences
Catalogue: LS-B3434

total number of products: 19

souris monoclonal (PC10)
Réactivité: humain, rat
application: Western blot, immunoprécipitation, immunohistochemistry - paraffin section

Human Breast (formalin-fixed, paraffin-embedded) stained with PCNA antibody LS-B3434 followed by biotinylated anti-mouse IgG secondary antibody LS-D2, alkaline phosphatase-streptavidin and chromogen.

Human Small Intestine (formalin-fixed, paraffin-embedded) stained with PCNA antibody LS-B3434 followed by biotinylated anti-mouse IgG secondary antibody LS-D2, alkaline phosphatase-streptavidin and chromogen.

Human Placenta (formalin-fixed, paraffin-embedded) stained with PCNA antibody LS-B3434 followed by biotinylated anti-mouse IgG secondary antibody LS-D2, alkaline phosphatase-streptavidin and chromogen.
quantité:
Prix:
fournisseur

Anti-PCNA Antibody IHC-plus™ LS-B4230
LifeSpan Biosciences
Catalogue: LS-B4230

total number of products: 19

souris monoclonal
Réactivité: humain, rat
application: immunohistochemistry - paraffin section

Colon, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Placenta, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Tonsil, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)
quantité:
Prix:
fournisseur

Anti-PCNA Antibody LS-C9521
LifeSpan Biosciences
Catalogue: LS-C9521

total number of products: 19

souris monoclonal
Réactivité: humain, rat
application: ELISA

quantité:
Prix:
fournisseur

PCNA anticorps monoclonal(12D10)
Celltechgen
Catalogue: CYM3031

souris monoclonal (#12D10)
Réactivité: humain, souris, rat
application: Western blot

quantité: 100 µg
Prix: 239 USD
fournisseur

PCNA anticorps
ProSci
Catalogue: 31-033

lapin polyclonal
Réactivité: humain, souris, rat, chien
application: Western blot, ELISA, immunohistochimie

quantité: 100 ug
Prix: 250 USD
fournisseur

Anti-PCNA Antibody (Monoclonal, PC 10)
Boster
Catalogue: MA1083

souris monoclonal (PC 10)
Réactivité: humain, souris, rat
application: Western blot, immunocytochimie, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

quantité: 100 ug/vial
Prix: 200 USD
fournisseur

PCNA anticorps
Rockland Immunochemicals
Catalogue: 600-401-968

lapin polyclonal
Réactivité: humain, souris, rat, chien, poulet, vaches
application: Western blot, ELISA

Western blot using Rockland's affinity purified anti-PCNA antibody shows detection of PCNA protein in HEK293 (lane 1) and Jurkat (lane 2) whole cell extracts. Approximately 25 ug of lysate was loaded per lane onto a 4-20% gradient gel followed by transfer to nitrocellulose. After blocking, the membrane was incubated with the primary antibody diluted to 1:1000. The membrane was washed and reacted with a 1:10,000 dilution of IRDye® 800 Conjugated Affinity Purified Goat-anti-Rabbit IgG [H&L] MX10 (611-132-122) (800 nm channel, green). Molecular weight estimation was made by comparison to prestained MW markers indicated at the right (lane M, 700 nm channel, red). Other detection systems will yield similar results.
quantité: 100 ug
Prix: 329.00 USD
fournisseur

PCNA, Proliferating Cell Nuclear Antigen
BioLogo
Catalogue: PC500

souris monoclonal (PC10)
Réactivité: humain, rat
application: immunohistochemistry - paraffin section

quantité: 5 ml
Prix: 150 USD
fournisseur

PCNA monoclonal antibody (M04), clone S1
Abnova
Catalogue: H00005111-M04

total number of products: 10

souris monoclonal (S1)
Réactivité: humain, souris, rat
application: Western blot, ELISA

quantité: 100 ug
Prix:
fournisseur

PCNA anticorps monoclonal
Abnova
Catalogue: MAB0293

total number of products: 10

souris monoclonal
Réactivité: humain, souris, rat
application: Western blot

quantité: 100 ug
Prix:
fournisseur

PCNA monoclonal antibody, clone IML-83
Abnova
Catalogue: MAB1524

total number of products: 10

souris monoclonal (IML-83)
Réactivité: humain, souris, rat
application: Western blot, immunocytochimie, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

quantité: 100 ug
Prix:
fournisseur

PCNA (Proliferating Cell Nuclear Antigen)
US Biological
Catalogue: P3115-05

souris monoclonal (0.T.109)
Réactivité: rat
application: ELISA

quantité: 100 ug
Prix: 478 USD
fournisseur

PCNA (Proliferating Cell Nuclear Antigen)
US Biological
Catalogue: P3115-10

souris monoclonal (0.N.508)
Réactivité: rat
application: Western blot, immunohistochimie, immunoprécipitation, cytométrie en flux

quantité: 500 ul
Prix: 459 USD
fournisseur

Anti-PCNA Antibody, clone PC10
EMD Millipore
Catalogue: MAB424

total number of products: 6

souris monoclonal (PC10)
Réactivité: humain, souris, rat, poisson-zèbre
application: Western blot, ELISA, immunohistochimie, immunocytochimie, immunoprécipitation, cytométrie en flux, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 49

quantité: 500 µg
Prix:
fournisseur

PCNA (PC10) Mouse mAb
Cell Signaling Technology
Catalogue: 2586

total number of products: 2

souris monoclonal (PC10)
Réactivité: humain, souris, rat, vaches
application: Western blot, immunohistochimie, immunocytochimie, immunoprécipitation, cytométrie en flux, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 83

quantité:
Prix:
fournisseur

PCNA
BD Biosciences
Catalogue: 610664

total number of products: 2

souris monoclonal (24/PCNA)
Réactivité: humain, souris, rat, chien
application: Western blot, immunohistochimie, immunocytochimie
citations: 5

quantité: 50 µg
Prix: 207.00 USD
fournisseur

PCNA anticorps
Abbiotec
Catalogue: 251790

souris monoclonal
Réactivité: humain, souris, rat
application: Western blot, ELISA, immunohistochimie, immunocytochimie

The PCNA Antibody is used in Western blot to detect PCNA in MCF7 cells.
quantité: 0.1 mg
Prix: 265 USD
fournisseur

Anti-PCNA antibody produced in rabbit
Sigma-Aldrich
Catalogue: AV03018

total number of products: 2

lapin polyclonal
Réactivité: humain, souris, rat, chien, vaches, poisson-zèbre
application: Western blot, immunohistochimie

quantité:
Prix:
fournisseur

Mouse Anti-Rat PCNA Clone PC10 mAb
Cell Sciences
Catalogue: MON6004

souris monoclonal (PC10)
Réactivité: rat

quantité: 1 ml
Prix: 480 USD
fournisseur

Goat anti-PCNA (aa111-122) Antibody
Everest Biotech
Catalogue: EB11651

total number of products: 2

chèvre polyclonal
Réactivité: humain, souris, rat, chien, vaches
application: Western blot

EB11651 (0.05ug/ml) staining of Jurkat lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
quantité: 100 ug in 200 ul
Prix: 315 USD
fournisseur